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Infectious
bacterial disease
actinomycosis
A 45-year-old male presents to an outpatient clinic with a progressively worsening right-sided facial swelling and discomfort over the past month. He reports intermittent difficulty with chewing and, occasionally, a sensation of stiffness in his jaw. He recalls a minor dental procedure on a posterior molar approximately three months prior, which seemed uncomplicated at the time. His past medical history includes essential hypertension and well-controlled type 2 diabetes. He is a social drinker and has no history of smoking. He works as a self-employed carpenter. On examination, his temperature is 38.00C (100.40F), blood pressure 130/70 mmHg, pulse 98/min, and respirations 16/min. Inspection reveals a subtle reddish-brown discoloration on the right lower jaw. Palpation reveals a firm, indurated area measuring approximately 4x5 cm, just inferior to the angle of the right mandible, with a small, pinpoint opening from which a yellowish, granular discharge is evident. There is no significant tenderness to palpation, but limited mouth opening is noted. A Gram stain of the exudate shows Gram-positive filamentous rods, and cultures are pending. What is the most likely diagnosis and the most appropriate initial pharmacological management strategy?
| Lab Parameter | Value | Reference Range |
|---|---|---|
| White Blood Cell Count | 12.5 x 10^9/L | 4.0-11.0 x 10^9/L |
| Neutrophils | 75% | 40-75% |
| C-reactive protein (CRP) | 25 mg/L | < 5 mg/L |

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